For B2B companies, the challenge often lies in finding the right strategy and choosing marketing efforts that not only connect with the right audience but also generate sustainable growth. Partnering with a capable B2B marketing agency is key to solving this challenge, offering the expertise and resources needed to turn prospects into revenue.
A strong B2B marketing agency brings valuable insights and proven strategies to the table. While the initial investment may seem significant, it can lead to higher returns, more efficient lead generation, and time savings that can ultimately reduce costs.
To help you navigate this decision, we’ve highlighted 13 leading B2B marketing agencies in 2025 that are known for delivering tangible results and supporting businesses in achieving their growth goals.
At the top of this list—and for good reason—The frank Agency sets the standard for what a health care marketing agency should be. With over 40 years of experience, they bring strategy, execution, and results under one roof. In an industry where trust, compliance, and clarity are non-negotiable, The frank Agency delivers on all fronts.
Their work goes beyond surface-level tactics. From paid media and SEO to demand generation and marketing automation, they engineer campaigns that don’t just look good—they drive real outcomes for healthcare brands navigating competitive and regulated spaces.
Year Founded: 1981
Office Location: Leawood, KS
Key Services: Social Media Marketing Campaigns, Search Engine Optimization, Conversion Optimization, Search Engine Marketing services, SEO Copywriting, Shopify SEO, Ecommerce SEO, Local SEO, SEO Audit, Link Building, B2B SEO, Enterprise SEO, Content Marketing, Email, Video, Creative Services, Website Development.
Top Clients: Caterpillar, Mercedes- Benz, Washburn University, Home Center Outlet, Kansas City Board of Public Utilities, ADS Dental Transitions, Watson Brown Sales, Western Practice Sales, Consani Associates, Help Hope Live
Case Studies: View all case studies
Echo-Factory brings a creative-first approach to industries that often feel anything but. As a healthcare digital marketing agency, they understand that building trust with patients isn’t just about compliance—it’s about connection. Their team helps healthcare brands clarify their messaging, differentiate themselves, and grow in competitive markets.
With roots in advertising and expansion into full-funnel marketing strategy, Echo-Factory blends branding with performance. Their work spans healthcare providers, medtech startups, and everything in between—tailored to move the needle for complex businesses in evolving spaces.
Year Founded: 2008
Office Location: Pasadena, CA
Key Services: Branding, Social Media Marketing, Digital PR, Paid Search Marketing, Website Development
Top Clients: Huntington Hospital / Cedars Sinai, Proponent
Case Studies: View all case studies
ChappellRoberts is a brand-led healthcare marketing firm with deep experience in helping health systems and nonprofit providers connect with communities. Their strength lies in combining insight-driven strategy with emotionally intelligent storytelling—turning complex healthcare topics into messages that move people.
With a focus on building long-term brand value, they help healthcare organizations stand out in saturated markets. From rebranding hospitals to launching integrated campaigns, their work reflects a strong grasp of both mission and market dynamics.
Year Founded: 1978
Office Location: Tampa, FL
Key Services: Branding, Integrated Advertising, Research, Digital PR, Website Development, Video Marketing
Top Clients: AdventHealth, USF Health, Florida Hospital, Sage Dental
Case Studies: View all case studies
Quaintise specializes in results-driven marketing for the healthcare sector, blending strategy and storytelling to deliver measurable outcomes. As a boutique healthcare marketing agency, they work closely with clients to refine messaging, enhance brand visibility, and drive patient engagement.
Their campaigns leverage data-backed insights, ensuring every effort aligns with business goals. From hospitals to private practices, Quaintise has a reputation for making healthcare brands more approachable, relatable, and competitive.
Year Founded: 2003
Office Location: Santa Monica, CA
Key Services: Marketing Automation Using GenAI, Health and Wellness Marketing, Brand Strategy, Healthcare Public Relations, Advertising Campaigns, Video, Brochure Design, Website Design and Development
Top Clients: HPV Hub, Women’s Health Arizona, EcoNugenics, Ketamine Clinics
Case Studies: View all case studies
Just Digital Inc. focuses on simplicity, clarity, and conversion. They’re a marketing agency that helps healthcare professionals streamline their online presence and generate leads through strategic branding and digital execution. Their sweet spot is working with private practices and small to mid-sized healthcare businesses that need results without the overhead.
From building conversion-focused websites to running ad campaigns that actually deliver, Just Digital offers practical solutions that get to the point—fast.
Year Founded: 2012
Office Location: Beverly Hills, CA
Key Services: Email Marketing, SEO, Social Media Marketing, Copywriting, Google Ads, Facebook Ads, Website Design and Development, Shopify Website Design
Top Clients: Integrative Wellbeing Institute, VeraVia, The Pimple Place
Case Studies: View all case studies
Intrepy is a specialized healthcare marketing agency built specifically for medical practices. Their focus is narrow by design—they don’t try to serve everyone. Instead, they go deep into patient acquisition strategies, reputation management, and physician branding to help providers grow sustainably in a crowded market.
Their strength lies in combining modern marketing tactics with industry-specific expertise, making them a strong partner for practices ready to invest in long-term growth.
Year Founded: 2014
Office Location: Orlando, FL
Key Services: Medical SEO, Healthcare PPC, Medical Website Design, Healthcare Social Media Marketing, Facebook Ads, Marketing Automation, Physician Reputation Management, Medical Graphic Design
Top Clients: Agility Orthopedics, TOA Park West Surgery Center, Comprehensive Orthopaedics, Spine Associates
Case Studies: View all case studies
Thrive brings a broad digital skill set to the table, with a dedicated vertical for healthcare clients. While not exclusively a healthcare digital marketing agency, they’ve built a solid track record in the space—helping clinics, urgent care centers, and wellness brands grow through data-driven campaigns.
Their strength is in execution. From SEO and paid ads to website design and social media, Thrive delivers full-service marketing with clear performance metrics and scalable strategies.
Year Founded: 2005
Office Location: Arlington, TX (Headquarters), with teams across 34 states and 10 countries
Key Services: Google Ads, Bing Ads, PPC Management, Display Advertising, Retargeting, Programmatic Advertising.
Top Clients: Tavistock Group, Hurom, Ready Seal, Austin College, Open Connectivity Foundation.
Case Studies: View all case studies
Elevation is a B2B-focused agency with deep experience across highly technical industries—including healthcare. While not a traditional healthcare marketing company, their ability to simplify complex messaging and drive results makes them a solid option for healthcare tech, pharma, and med device companies targeting professional buyers.
Their approach leans heavily into research, content, and strategy—ideal for organizations that need to educate as much as they need to sell.
Year Founded: 1999
Office Location: San Francisco, CA
Key Services: Content Marketing, Social Media Marketing, Video Production, Web Design, SEO, PPC Advertising, Analytics and Reporting, Email Marketing, Influencer Marketing, Direct Mail Marketing, Customer Relationship Management, Lead Generation, Sales Funnel Optimization, Account-Based Marketing (ABM), Conversion Rate Optimization
Top Clients: Pfizer, JDRF, Anthem
Case Studies: View all case studies
Typoductions is a boutique agency focused on healthcare and medical marketing. With services ranging from video production to digital strategy, they help providers and health systems build strong visual identities and communicate clearly in a crowded space. Their work leans heavily on storytelling—particularly through video—to humanize complex medical services.
While smaller in scale, Typoductions delivers specialized work tailored to the unique communication needs of healthcare brands.
Year Founded: 2015
Office Location: Pomona, NY
Key Services: Social Media, Online Reputation, Video Marketing, Graphic Design, Website Development, Email Marketing,
Top Clients: Vanguard Healthcare Services, Anchor Health Pediatric Hospice
Case Studies: View all case studies
WebFX is a large-scale digital agency with a wide industry reach—including healthcare. As a healthcare advertising agency, they focus on driving measurable growth through SEO, paid search, and conversion rate optimization. Their strength lies in scale, offering access to deep analytics, custom reporting, and a full-stack marketing tech platform.
For healthcare organizations looking to grow fast with data-heavy support, WebFX offers the tools and infrastructure to compete at scale.
Year Founded: 1996
Office Location: Harrisburg, PA
Key Services: Search Engine Marketing, SEO, Conversion Rate Optimization, Web Design & Development, Social Media Marketing, Content Marketing, Paid Search Management.
Top Clients: Hurst Pediatric Dentistry, Kennedy Valve, LendKey Technologies, Giant Food Stores, Penn State, Hershey's.
Case Studies: View all case studies
Healthcare Success is a full-service healthcare marketing agency with decades of experience helping hospitals, group practices, and health systems increase patient volume. Their approach combines traditional marketing with digital execution—making them a fit for providers who want broad visibility across both offline and online channels.
They offer deep healthcare-specific expertise, especially in competitive regional markets where strategic positioning and consistent messaging make all the difference.
Year Founded: 2006
Office Location: Irvine, CA
Key Services: Content Marketing, SEO Optimization, PPC Advertising, Social Media Marketing, Website Design, Reputation Management, Patient Referral Marketing, Video Production, Marketing Pharmaceutical Company
Top Clients: Pomona Valley Health Centers, Thomson Memory Center, Mountain View Medical Center
Case Studies: View all case studies
High Level Marketing works with healthcare practices that need more than just visibility—they need results. The agency focuses on lead generation through SEO, paid ads, and conversion-optimized websites. Their approach is process-driven, making them a solid option for private practices, urgent care centers, and specialty clinics looking for consistent growth.
Their strength is in delivering marketing infrastructure that scales—especially for multi-location providers who need local reach with centralized control.
Year Founded: 2009
Office Location: Montgomery, AL
Key Services: Search Engine Marketing, SEO, Web Design & Development, Social Media Marketing, Content Marketing, Email Marketing, Branding
Top Clients: PDO Max, Sylacauga Obstetrics & Gynecology, Skin Wellness
Case Studies: View all case studies
EVERSANA INTOUCH is a large, enterprise-level healthcare marketing agency that serves pharmaceutical, biotech, and life sciences companies. As part of the larger EVERSANA network, they bring integrated marketing and commercialization under one roof—connecting strategy, creative, data, and patient support for brands operating at global scale.
Best suited for enterprise healthcare companies, their strength lies in aligning brand objectives with real-world healthcare impact.
Year Founded: 1999
Office Location: Overland Park, KS
Key Services: Branding and Creative, Market Research and Insights, Multi-Channel Wellness Marketing, Sales & Marketing, Data Analytics, Patient Support, Healthcare Consulting
Top Clients: Evoke Pharma, Biogen, RVL Pharmaceuticals
Case Studies: View all case studies
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